Professor of Pharmacology at ICB-USP and a biologist by training, he has built his scientific career in cardiovascular pharmacology, focusing on how estrogen and aging modulate vascular function through pathways associated with oxidative stress and metabolic changes. The goal is to understand sex differences in the genesis of cardiovascular diseases. During his postdoctoral work at the School of Medicine of Ribeirão Preto and at Johns Hopkins University, he deepened his studies on arterial stiffness, estrogen signaling, and O-GlcNAc-mediated cellular stress responses. The lab he leads thus seeks to understand how age, sex, and O-GlcNAc influence vascular adaptation to stress, aiming to develop new cellular reprogramming strategies and advance the understanding of cardiovascular diseases.
